Reducing Risks of Exposure to Chemical Compounds in the Laboratory
Chemical compounds are integral in drug research and development, providing increasingly effective medicines with lower doses and longer-term benefits. However, scientists face an increased risk of exposure to these chemical compounds due to their pharmacological effects at low levels, even down to nanogram quantities. The risk of exposure occurs through airborne particulates, skin contact, and inadvertent contact with mucous membranes.
Airborne Contamination
Airborne particulates, which are invisible to the naked eye, can be released when manipulating drug powders. Particles less than 10 μm in size can reach deep inside the alveolar regions of the lung, allowing the drug to be quickly absorbed into the bloodstream. Skin contact with the active drug, particularly in the presence of organic solvents, enhances dermal absorption. Similarly, contact with compound residues on mucous membranes can quickly introduce active drugs into the bloodstream.
Advancements in Air Monitoring and Analytical Detection Techniques
To address this risk, advancements in air monitoring instrumentation and analytical detection techniques have enabled the accurate measurement of airborne contamination levels during drug manipulation processes in the laboratory. This provides Safety Managers and Occupational Hygienists with valuable exposure data, allowing for effective safety controls to be implemented.
Containment Technology as a Solution
One such control measure is the use of containment technology, which provides a safe working environment for scientists without limiting their ability to carry out their work efficiently. Containment technology can reduce airborne contamination levels and prevent skin and mucous membrane contact with hazardous materials. In addition, proper training and education on safe handling practices, the use of personal protective equipment, and regular cleaning and maintenance of laboratory equipment can also minimise the risk of exposure to chemicals.
Collaborating for Effective Safety Controls in Laboratories
In conclusion, with the increasing use of chemical compounds in drug research and development, it is crucial for Occupational Hygienists, Safety Managers, Facilities Managers, Laboratory Managers, and Scientists to work together to implement effective safety controls. The use of containment technology, coupled with proper training and education, can significantly reduce the potential for exposure to hazardous materials, including active pharmaceutical ingredients, in the laboratory environment.
Providing Tailored Safety Solutions
At Envirosafe Ireland, we understand the importance of workplace safety, which is why we offer a range of safety equipment and solutions tailored to meet each client’s specific needs.
Founded in 2010 by a team of experts with over 30 years of experience in the pharmaceutical, laboratory, and gas industries, Envirosafe Ireland is a trusted name. In addition to providing high-quality products, we offer customised solutions to ensure our clients have access to the most effective safety measures for their unique needs. Whether you’re looking for containment technology or other safety solutions, our team of experts is ready to help.
To learn more about our products and services, simply fill out our contact form, call us at +353879170231, or send an email to info@envirosafeireland.ie. Trust the experts at Envirosafe Ireland to help you create a safer working environment for your business.
